Szyfter et al (2012) report therapeutic results from 103 patients treated for otogenic brain abscess (primarily located within the temporal lobe and generally due to chronic inflammation of the middle ear) across three time periods (1953 to 1977, 1978 to 1989, and 1990 to 2011). They report mortality rates dropped dramatically from 35 percent in the first reported time period (1953 to 1977) to 3 percent in the most recent reported time period (1990 to 2011). Szyfter et al report multiple factors have impacted and contributed to the impressive gains with respect to therapeutic treatments including improved pediatric and otologic care, increased awareness, efficient antibiotics, and quicker diagnosis and surgical management of chronic ears with cholesteatoma.
For More Information, References, and Recommendations
Szyfter W, Kruk-Zagajewska A, Borucki L, Bartochowska A. (2012) Evolution in Management of Otogenic Brain Abscess. Otology & Neurotology 33(3):393-395.