Unilateral Hearing Loss
Altered levels of activity in the auditory cortex may contribute to some auditory processing deficits observed in patients with unilateral conductive hearing loss (CHL), according to Duke University researchers. They studied the effects of unilateral hearing loss on 2-deoxyglucose (2-DG) uptake in the central auditory system. To do so, they injected young gerbils with 2-DG three weeks after the animals had experienced a CHL or cochlear ablation (CA). The animals were then exposed to various auditory stimuli while researchers measured 2-DG uptake in the inferior colliculus (IC), medial geniculate, and auditory cortex (fields AI and AAF) of both sides of the brain in experimental and control animals. Results of the study showed experimental animals demonstrated significantly higher levels of uptake in the IC contralateral to the CHL or CA ear and in AAF contralateral to the CHL ear.
Surgery Litigation & Law Weekly (05/16/08)
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