In their new book, CHARGE Syndrome, Hartshorne, Hefner, Davenport, and Thelin (2011, Plural Publishing) offer an extraordinarily in-depth, authoritative and comprehensive discussion of CHARGE Syndrome.
CHARGE is an acronym, “C” represents coloboma, “H” represents heart, “A” represents atresia, “R” represents retardation of growth and development, “G” represents genitourinary and “E” represents ear anomalies and hearing loss. CHARGE syndrome is caused by a defect in one or more genes (including CHD7) which is of critical importance during embryonic development.